Chloromethyl Methyl Ether → ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-1-methoxymethyl-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate

HRID 1252902ノート

反応式

HRID 1252902 の反応式
[Cl:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]2[C:18](=[O:19])[C:17]3[CH2:20][CH2:21][CH2:22][C:16]=3[NH:15][C:14]2=[O:23])=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].[CH3:24][O:25][CH2:26]Cl>CN(C)C=O>[Cl:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]2[C:18](=[O:19])[C:17]3[CH2:20][CH2:21][CH2:22][C:16]=3[N:15]([CH2:24][O:25][CH3:26])[C:14]2=[O:23])=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5]

参加物

4

反応物 2

HCID 7864Chloromethyl Methyl EtherHCID 21270732ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate

生成物 1

HCID 20130644ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-1-methoxymethyl-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

using ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate and chlorodimethyl ether in dimethylformamide there is obtained ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-1-methoxymethyl-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate, m.p. 103°-106° C.,

出典と根拠

ORDレコード
ord-c69bb462b371497788604fa4fc4eb5d1
出典データセット
uspto-grants-1988_05
特許番号
US04746352

反応ノート

読み込み中…