Hydrochloric Acid → 1,5-Dichloro-3,3-dimethylpentan-2-one

HRID 1253276ノート

反応式

HRID 1253276 の反応式
[ClH:1].[Cl:2][CH:3]=[C:4]1[C:8]([CH3:10])([CH3:9])[CH2:7][CH2:6][O:5]1>>[Cl:2][CH2:3][C:4](=[O:5])[C:8]([CH3:10])([CH3:9])[CH2:7][CH2:6][Cl:1]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 536634572-(Chloromethylidene)-3,3-dimethyloxolane

生成物 1

HCID 132542791,5-Dichloro-3,3-dimethylpentan-2-one収率 90%

実験手順

A powerful stream of hydrogen chloride gas from a cylinder is passed into 476 g (3.25 moles) of 2-chloromethylene-3,3-dimethyltetrahydrofuran, with ice-cooling. The gas is absorbed completely and the internal temperature rises up to 30° C. After complete saturation with hydrogen chloride, the reaction mixture is subsequently stirred at room temperature for 2 hours. Excess hydrogen chloride is initially stripped off using a water pump, and the mixture is then distilled under a high vacuum. 531 g (90% of theory) of 1,5-dichloro-3,3-dimethyl-2-pentanone of boiling point 85°-90° C./0.3 mbar are obtained. ##STR103##

後処理

  1. temperaturecooling
  2. customThe gas is absorbed completely
  3. customrises up to 30° C
  4. distillationthe mixture is then distilled under a high vacuum

出典と根拠

ORDレコード
ord-2b13a0f40e054480bc8939e84b0f2be9
出典データセット
uspto-grants-1988_05
特許番号
US04748249

反応ノート

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