Phenyl isocyanate → HCID 14156418、化合物
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]3[C:7](=[CH:23][N:24]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[N:25]=3)[C:8]([CH2:12][CH2:13][NH:14][C:15]3[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=3)=[N:9][C:10]=2[CH:11]=1.[C:32]1([N:38]=[C:39]=[O:40])[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]3[C:7](=[CH:23][N:24]([C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=4)[N:25]=3)[C:8]([CH2:12][CH2:13][N:14]([C:15]3[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=3)[C:39]([NH:38][C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)=[O:40])=[N:9][C:10]=2[CH:11]=1参加物
4
実験手順
A solution of 100 mg (0.24 mmol) of the compound of Example 1, 150 mg (1.26 mmol) of phenylisocyanate, and 8 ml of methylene chloride is stirred at ambient temperature for four days. The resulting precipitate is collected and triturated with ether to afford 88 mg (68%) of title compound: IR (KBr) 3440, 2240, 1670, 1605, 1520, 1510, and 1440 cm-1 ; NMR (DMSO-d6) δ 9.56 (s, 1H), 8.72 (s, 1H, exchangeable), 8.48-6.96 (complex m, 17H), 4.46 (t, 2H), and 3.5 (t, 2H).