HCID 59382877、化合物 → HCID 59383036、化合物
反応式
[F:1][C:2]([F:25])([F:24])[C:3]([CH:11]1[CH2:16][CH2:15][CH2:14][N:13](C(OC(C)(C)C)=O)[CH2:12]1)([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH3:9]>C(O)(C(F)(F)F)=O.ClCCl>[F:25][C:2]([F:1])([F:24])[C:3]([CH:11]1[CH2:16][CH2:15][CH2:14][NH:13][CH2:12]1)([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH3:9]参加物
3
実験手順
Tert-butyl 3-(1,1,1-trifluoro-2-hydroxy-6-methoxyhexan-2-yl)piperidine-1-carboxylate (20 mg) was dissolved in 1:1 TFA/dichloromethane (4 mL). The mixture was stirred for 30 min. The mixture was concentrated to afford 1,1,1-trifluoro-6-methoxy-2-(piperidin-3-yl)hexan-2-ol which was used without purification.
後処理
- concentrationThe mixture was concentrated
出典と根拠
- ORDレコード
- ord-2c4abd4d20094ba384ebc54b27feb14b
- 出典データセット
- uspto-grants-2013_06
- 特許番号
- US08455521B2
反応ノート
読み込み中…