N,N'-Dimethylethylenediamine → 1-(5,6-Diphenyl-pyrazin-2-yl)-ethanone

HRID 12567

反応式

HRID 12567 の反応式
[C:1]1([C:7]2[N:8]=[CH:9][C:10]([C:19]([O:21]C)=O)=[N:11][C:12]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:23][Al](C)C.CNCCNC>C1(C)C=CC=CC=1>[C:1]1([C:7]2[N:8]=[CH:9][C:10]([C:19](=[O:21])[CH3:23])=[N:11][C:12]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 3

HCID 8070N,N'-DimethylethylenediamineHCID 16682925TrimethylaluminumHCID 25033170Methyl 5,6-Diphenyl-pyrazine-2-carboxylate2 回

生成物 1

HCID 155003941-(5,6-Diphenyl-pyrazin-2-yl)-ethanone

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Following General Procedure O, methyl 5,6-diphenyl-pyrazine-2-carboxylate (Compound 93, 83 mg, 0.29 mmol), Me3Al (0.4 ml, 2M in toluene), DMEDA (28 mg, 0.32 mmol) in toluene was reacted to afford the title compound.

後処理

  1. customwas reacted

出典と根拠

ORDレコード
ord-a4b8b340cd66468184e61d265b7d3439
出典データセット
uspto-grants-2010_06
特許番号
US07728014B2

関連ノート

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