化工社化工社 化学情報印刷レポート · 研究参考用
N,N'-Dimethylethylenediamine → 1-(5,6-Diphenyl-pyrazin-2-yl)-propan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N'-Dimethylethylenediamine | HCID 8070 | — |
| 反応物 | Triethylaluminum | HCID 16682930 | — |
| 反応物 | Methyl 5,6-Diphenyl-pyrazine-2-carboxylate | HCID 25033170 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-(5,6-Diphenyl-pyrazin-2-yl)-propan-1-one | HCID 11231543 | — |
反応手順
Following General Procedure O, methyl 5,6-diphenyl-pyrazine-2-carboxylate (Compound 93) (92 mg, 0.32 mmol), Et3Al (0.9 ml, 1M in hexane), DMEDA (38 mg, 0.35 mmol) in toluene was reacted to afford the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728014B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-c266ff78267141f78cd7efceb38cee8f |
| 出典メモ | uspto-grants-2010_06 |