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Allyl Alcohol → 4-Allyloxymethyl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Allyl Alcohol | HCID 7858 | — |
| 反応物 | 4-(Bromomethyl)benzoic acid | HCID 22599 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 4-But-3-enyloxymethyl-benzoic acid | HCID 22136996 | — |
| 生成物 | 4-Allyloxymethyl-benzoic acid | HCID 23186913 | — |
反応手順
The reaction of allyl alcohol and 4-Bromomethyl-benzoic acid in the presence of sodium hydride was performed as described for Compound 33 to give 4-Allyloxymethyl-benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 7.91 (d, J=8.3, 2 arom. H); 7.42 (d, J=8.3, 2 arom.H); 5.90 (m, —CHCH2); 5.30, 5.18 (2 d-like, —CH═CH2); 4.54 (s, —OCH2—C6H4); 4.01 (2 d-like, CH2═CHCH2O). 13C-NMR (100 MHz, d6-DMSO): 161.18 (—C═O); 143.48; 134.97; 129.95; 129.31 (2 arom.C); 127.11 (2 arom.C); 116.63; 70.64 (2 C).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08466199B2 |
| 出典データセット | uspto-grants-2013_06 |
| ORD ID | ord-03bb24bae0054ee5940aba84f32d59ef |
| 出典メモ | uspto-grants-2013_06 |