N-[3-(4-Hydroxyphenyl)-1-methylpropyl]acetamide → N-(1-Methyl-3-{4-[5-(tetrahydrofuran-3-yloxy)pyridin-2-yloxy]phenyl}propyl)acetamide

反応式

[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH:10]([NH:12][C:13](=[O:15])[CH3:14])[CH3:11])=[CH:4][CH:3]=1.Cl[C:17]1[CH:22]=[CH:21][C:20]([O:23][CH:24]2[CH2:28][CH2:27][O:26][CH2:25]2)=[CH:19][N:18]=1>>[CH3:11][CH:10]([NH:12][C:13](=[O:15])[CH3:14])[CH2:9][CH2:8][C:5]1[CH:4]=[CH:3][C:2]([O:1][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH:24]3[CH2:28][CH2:27][O:26][CH2:25]3)=[CH:19][N:18]=2)=[CH:7][CH:6]=1

参加物

反応物 2

HCID 59956161N-[3-(4-Hydroxyphenyl)-1-methylpropyl]acetamide

HCID 717778752-Chloro-5-(tetrahydrofuran-3-yloxy)pyridine

生成物 1

HCID 44608788N-(1-Methyl-3-{4-[5-(tetrahydrofuran-3-yloxy)pyridin-2-yloxy]phenyl}propyl)acetamide

実験手順

N-[3-(4-Hydroxyphenyl)-1-methylpropyl]acetamide was reacted with 2-chloro-5-(tetrahydrofuran-3-yloxy)pyridine in analogy to example 2c.

出典と根拠

ORDレコード: ord-d9c23b0158c04c4fa197472bc055c942
出典データセット: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08470841B2

反応ノート

読み込み中…