4-Fluoro-3-(trifluoromethyl)benzaldehyde → 1-Bromomethyl-4-ethanesulfonyl-2-trifluoromethyl-benzene
反応式
[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[CH:5][C:4]=1Cl.FC1C=CC(C=O)=CC=1[C:23]([F:26])([F:25])[F:24].[CH2:27](S([O-])=O)C.[Na+]>>[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH2:12][CH3:27])(=[O:11])=[O:10])=[CH:5][C:4]=1[C:23]([F:26])([F:25])[F:24]参加物
4
実験手順
The titled compound is prepared analogously to 1-bromomethyl-2-chloro-4-methanesulfonyl-benzene by replacing 2-chloro-4-fluorobenzaldehyde (step 90a) with 4-fluoro-3-trifluoromethylbenzaldehyde and by replacing sodium methanesulfinate with sodium ethanesulfinate.
出典と根拠
- ORDレコード
- ord-7757de08df804fce9243b0f9320eb06c
- 出典データセット
- uspto-grants-2013_06
- 特許番号
- US08470848B2
反応ノート
読み込み中…