6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine → 4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine
反応式
[Br:1][C:2]1[C:3]([O:11][C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][C:13]=2[F:21])=[C:4]2[S:10][CH:9]=[CH:8][C:5]2=[N:6][CH:7]=1.N1C2=C(OC3C=CC(N)=CC=3F)N=CC=C2C=C1>>[Br:1][C:2]1[C:3]([O:11][C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][C:13]=2[F:21])=[C:4]2[S:10][CH:9]=[CH:8][C:5]2=[N:6][CH:7]=1参加物
3
実験手順
Starting from the compound 272 and following the procedure described above for the synthesis of compound 261 (scheme 59, example 218, step 3), title compound 273 was obtained in 92% yield as a light brown solid. MS (m/z): 340.0(M+H).
出典と根拠
- ORDレコード
- ord-2d97703c2e0a497c9573be5b3511c661
- 出典データセット
- uspto-grants-2013_06
- 特許番号
- US08470850B2
反応ノート
読み込み中…