Dichloromethane → N-[(1R,3S)-3-isopropyl-3-(4-[6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-ylcarbonyl)cyclopentyl]-3-methyltetrahydro-2H-pyran-4-amine

反応式

[CH:1]([C@:4]1([C:17]([N:19]2[CH2:24][CH2:23][N:22]([C:25]3[CH:30]=[C:29]([C:31]([F:34])([F:33])[F:32])[N:28]=[CH:27][N:26]=3)[CH2:21][CH2:20]2)=[O:18])[CH2:8][CH2:7][C@@H:6]([NH:9][C:10](=O)OC(C)(C)C)[CH2:5]1)([CH3:3])[CH3:2].O1[CH2:40][CH2:39][O:38][CH2:37][CH2:36]1.[CH2:41](Cl)Cl>Cl>[CH:1]([C@:4]1([C:17]([N:19]2[CH2:20][CH2:21][N:22]([C:25]3[CH:30]=[C:29]([C:31]([F:34])([F:33])[F:32])[N:28]=[CH:27][N:26]=3)[CH2:23][CH2:24]2)=[O:18])[CH2:8][CH2:7][C@@H:6]([NH:9][CH:10]2[CH2:36][CH2:37][O:38][CH2:39][CH:40]2[CH3:41])[CH2:5]1)([CH3:2])[CH3:3]