Dimethylformamide → 6-chloro-4-ethyl-4-(4-cyanophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

反応式

[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][C:7](=[O:12])[N:6]([CH2:13][C:14]([F:15])([F:16])[F:17])[C:5]2([c:18]1[cH:19][cH:20][c:21]([Br:24])[cH:22][cH:23]1)[CH2:25][CH3:26].[Cu:27][C:28]#[N:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][C:7](=[O:12])[N:6]([CH2:13][C:14]([F:15])([F:16])[F:17])[C:5]2([c:18]1[cH:19][cH:20][c:21]([C:28]#[N:29])[cH:22][cH:23]1)[CH2:25][CH3:26]

参加物

反応物 3

HCID 6228Dimethylformamide

HCID 118538166-chloro-4-ethyl-4-(4-bromophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

HCID 178418546HCID 178418546、化合物

生成物 1

HCID 118538176-chloro-4-ethyl-4-(4-cyanophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

出典と根拠

ORDレコード: ord-f15dadfc852d473ebd13fa969b71bc98
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…