Water → 2-Chloro-6-methyl-4-(2,5-dichloro-4-methylmercapto-phenoxy)-pyridine

HRID 1262783

反応式

HRID 1262783 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([S:8][CH3:9])[C:5]([Cl:10])=[CH:4][C:3]=1[O-:11].[K+].[Cl:13][C:14]1[CH:19]=[C:18](Cl)[CH:17]=[C:16]([CH3:21])[N:15]=1.O>CN(C)C=O>[Cl:13][C:14]1[CH:19]=[C:18]([O:11][C:3]2[CH:4]=[C:5]([Cl:10])[C:6]([S:8][CH3:9])=[CH:7][C:2]=2[Cl:1])[CH:17]=[C:16]([CH3:21])[N:15]=1

参加物

5

反応物 3

HCID 962WaterHCID 119590832,4-Dichloro-6-methylpyridineHCID 70505068Potassium 2,5-dichloro-4-methylmercapto-phenolate

生成物 1

HCID 130736682-Chloro-6-methyl-4-(2,5-dichloro-4-methylmercapto-phenoxy)-pyridine

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A solution of 25.5 gm (0.1 mol) of potassium 2,5-dichloro-4-methylmercapto-phenolate and 16.2 gm (0.1 mol) of 2,4-dichloro-6-methyl-pyridine in 100 ml of dimethylformamide was heated under reflux for 5 hours. It was then cooled and poured into 300 ml of water. The precipitate which separated out was recovered by suction filtration, washed with water, and recrystallized from isopropanol.

後処理

  1. temperatureunder reflux for 5 hours
  2. temperatureIt was then cooled
  3. customThe precipitate which separated out
  4. filtrationwas recovered by suction filtration
  5. washwashed with water
  6. customrecrystallized from isopropanol

出典と根拠

ORDレコード
ord-e9c59a82f7d346e99ef65f079b634475
出典データセット
uspto-grants-1984_06
特許番号
US04453972

関連ノート

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