5-(3,4-Dichlorobenzyl-carbamoyl)-thiophene-2-carboxylic acid → 5(3,4-Dichlorobenzylcarbamoyl)pyridine-2-carbonylchloride
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[CH2:5][NH:6][C:7]([C:9]1[CH:10]=[CH:11][C:12]([C:15](O)=[O:16])=[N:13][CH:14]=1)=[O:8].[Cl:22]C1C=C(C=CC=1Cl)CNC(C1SC(C(O)=O)=CC=1)=O>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[CH2:5][NH:6][C:7]([C:9]1[CH:10]=[CH:11][C:12]([C:15]([Cl:22])=[O:16])=[N:13][CH:14]=1)=[O:8]参加物
3
実験手順
Compound (13(b)) was treated in an analogous manner to compound (12(b)) in Example 12 to give 5(3,4-dichlorobenzylcarbamoyl)pyridine-2-carbonylchloride (13(c)) which was used crude in the next reaction.
出典と根拠
- ORDレコード
- ord-52baa47682b942eabd003fbf7fca1a71
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06541491B1
反応ノート
読み込み中…