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HRID 1265092作成日：2026年10月27日

trans-2-Phenylcyclopropyl isocyanate → N-{3-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-N'-[(1R*,2S)-2-phenylcyclopropyl]urea

https://huagongshe.com/reaction/1265092

反応式

関与物質

役割名称HCID仕込み量
反応物trans-2-Phenylcyclopropyl isocyanateHCID 255285—
反応物1-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amineHCID 21973836—
生成物N-{3-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-N'-[(1R*,2S)-2-phenylcyclopropyl]ureaHCID 20575810—

反応手順

Using the method of Examples 94-105, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 437.2674.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06545017B1
出典データセットuspto-grants-2003_04
ORD IDord-508c74f6262b4ec1a4d53093c7338599
出典メモuspto-grants-2003_04