N-[3-(2-bromoacetyl)phenyl]methanesulfonamide → (+/-)-N-[3-(2-bromo-1-hydroxyethyl)phenyl]methanesulfonamide
反応式
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:6]=1)=[O:4]>CO.C(Cl)(Cl)Cl>[Br:1][CH2:2][CH:3]([C:5]1[CH:6]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:9][CH:10]=1)[OH:4]参加物
3
実験手順
The above-identified compound (50.76 g) was obtained by processing Intermediate 14 (45 g) through reaction and after-treatment in accordance with the procedures of synthesis of Intermediate 41. Rf=0.27 (methanol/chloroform of 1/10).
後処理
- customthrough reaction
出典と根拠
- ORDレコード
- ord-3e5457bc3184484582942ecbb1c89b3d
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06545053B1
反応ノート
読み込み中…