Dimethylamine → (5-Dimethylamino-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester
反応式
[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12](Cl)[C:11]([F:15])=[CH:10][C:9]=1[N+:16]([O-:18])=[O:17])([CH3:4])([CH3:3])[CH3:2].[NH:20]([CH3:22])[CH3:21]>CS(C)=O>[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([N:20]([CH3:22])[CH3:21])[C:11]([F:15])=[CH:10][C:9]=1[N+:16]([O-:18])=[O:17])([CH3:4])([CH3:3])[CH3:2]参加物
4
実験手順
The title compound was prepared from (5-chloro-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example B6) (4.94 g, 17 mmol) and Me2NH (40% in H2O, 7.9M, 10.9 mL, 86 mmol) in DMSO (35 mL) at 23° C. according to the general procedure C. Obtained as a yellow solid (4.93 g).
出典と根拠
- ORDレコード
- ord-3f15e8ff6bd940e58f72cb258efab604
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06544985B2
反応ノート
読み込み中…