Dimethylamine → HCID 69688169、化合物

HRID 1265520ノート

反応式

HRID 1265520 の反応式
[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12](Cl)[C:11]([CH3:15])=[CH:10][C:9]=1[N+:16]([O-:18])=[O:17])([CH3:4])([CH3:3])[CH3:2].[CH3:20][NH:21][CH3:22]>CS(C)=O>[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([N:21]([CH3:22])[CH3:20])[C:11]([CH3:15])=[CH:10][C:9]=1[N+:16]([O-:18])=[O:17])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 2

HCID 674DimethylamineHCID 69486680Carbamic acid, (5-chloro-4-methyl-2-nitrophenyl)-, 1,1-dimethylethyl ester

生成物 1

HCID 69688169HCID 69688169、化合物

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

実験手順

The title compound was prepared from (5-chloro-4-methyl-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example B8) (3.5 g, 12.2 mmol) and dimethylamine (11 ml, 33% in EtOH, 61.0 mmol) in DMSO (35 mL) at 50° C. according to the general procedure C. Obtained as a yellow solid (3.50 g, 97%).

出典と根拠

ORDレコード
ord-ac0b4f6409c244cd96b64f2df8437ea5
出典データセット
uspto-grants-2003_04
特許番号
US06544985B2

反応ノート

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