Benzoic acid, 3-cyano-, methyl ester → 3-(3-Cyano-phenyl)-3-oxo-propionic acid tert-butyl ester

HRID 1266758

反応式

HRID 1266758 の反応式
[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[C:6]([O:8]C)=O)#[N:2].[C:13]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])(=[O:15])[CH3:14].[Li]>>[C:17]([O:16][C:13](=[O:15])[CH2:14][C:6]([C:5]1[CH:10]=[CH:11][CH:12]=[C:3]([C:1]#[N:2])[CH:4]=1)=[O:8])([CH3:20])([CH3:19])[CH3:18]

参加物

3

反応物 2

HCID 83554Benzoic acid, 3-cyano-, methyl esterHCID 86586795Lithium Tert-butyl Acetate

生成物 1

HCID 695928893-(3-Cyano-phenyl)-3-oxo-propionic acid tert-butyl ester

実験手順

The title compound was prepared from methyl 3-cyanobenzoate [CAS-No. 13531-48-1] by treatment with lithium tert.-butyl acetate according to general procedure K (method b). Obtained as a light brown oily semisolid.

後処理

  1. customObtained as a light brown oily semisolid

出典と根拠

ORDレコード
ord-d0ecf21e24d34a0d97700b83f8d24715
出典データセット
uspto-grants-2003_04
特許番号
US06548495B2

関連ノート

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