3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → 3-(3-Cyano-phenyl)-N-[5-(3-cyano-4-phenyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamide
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([N:11]2[CH:15]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:13]([C:22]#[N:23])=[CH:12]2)[CH:5]=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].CC1(C)[O:30][C:29]([C:31]2[CH:32]=[C:33]([CH:36]=[CH:37][CH:38]=2)[C:34]#[N:35])=[CH:28][C:27](=O)[O:26]1>>[C:34]([C:33]1[CH:32]=[C:31]([C:29](=[O:30])[CH2:28][C:27]([NH:1][C:2]2[CH:3]=[C:4]([N:11]3[CH:15]=[C:14]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=4)[C:13]([C:22]#[N:23])=[CH:12]3)[CH:5]=[CH:6][C:7]=2[N+:8]([O-:10])=[O:9])=[O:26])[CH:38]=[CH:37][CH:36]=1)#[N:35]参加物
3
実験手順
The title compound was prepared from 1-(3-amino-4-nitro-phenyl)-4-phenyl-1H-pyrrole-3-carbonitrile (Example E3) (254 mg, 0.835 mmol) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example L1) (210 mg, 0.919 mmol) according to the general procedure M. Obtained as an orange solid (287 mg).
出典と根拠
- ORDレコード
- ord-389b17cb314f47a1887701e8723da7b2
- 出典データセット