Hydrochloric Acid → 4'-Trifluoromethl-biphenyl-2-carboxylic Acid [4-[4-(3-cyano-benzyl)-piperazin-1-yl]-phenyl]-amide hydrochloride Salt

関与物質

反応手順

To a solution of 4′-trifluoromehtyl-biphenyl-2-carboxylic acid [4-[4-(3-cyano-benzyl)-piperazin-1-yl]-phenyl]-amide (0.2 g) in AcOEt (25 mL) was added 1N hydrochloric acid (0.9 mL) and the resulting solution was stirred at room temperature for 1.5 hours. The solution was then evaporated to dryness and the solid was recrystallized from AcOEt/hexane to give the title compound (0.18 g) as a white power.

情報源と証拠