O-Xylene → Methyl 1-methylcyclopropane-1-carboxylate
反応式
C1(C)C(C)=CC=CC=1.[Cl:9][CH2:10][CH2:11][CH:12]([CH3:17])[C:13]([O:15][CH3:16])=[O:14].C[O-].[Na+]>CO>[CH3:17][C:12]1([C:13]([O:15][CH3:16])=[O:14])[CH2:10][CH2:11]1.[Cl:9][CH2:10][CH2:11][CH:12]([CH3:17])[C:13]([O:15][CH3:16])=[O:14]参加物
6
反応条件
- 温度
- 150 °C
実験手順
contacting the xylene solution of methyl 4-chloro-2-methylbutyrate from step (3) with an sodium methoxide and heating at temperatures of about 100 to 200° C. which causes vaporization of (i) methanol as it is formed and (ii) methyl 1-methylcyclopropanecarboxylate as it is formed from methyl 4-chloro-2-methylbutyrate.
後処理
- customis formed
出典と根拠
- ORDレコード
- ord-06594cb39e2b46899741b890488f1755
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06552217B2
反応ノート
読み込み中…