Dicyclohexylcarbodiimide → 5,5-Dimethyl-8-(2-heptyl)-10-[4-(piperidino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride
反応式
[CH3:1][C:2]1([CH3:24])[C:19]2=[CH:20][CH:21]=[N:22][CH:23]=[C:18]2[C:5]2[C:6]([OH:17])=[CH:7][C:8]([CH:10]([CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:11])=[CH:9][C:4]=2[O:3]1.[ClH:25].[N:26]1([CH2:32][CH2:33][CH2:34][C:35](O)=[O:36])[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1.C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:25].[CH3:24][C:2]1([CH3:1])[C:19]2=[CH:20][CH:21]=[N:22][CH:23]=[C:18]2[C:5]2[C:6]([O:17][C:35](=[O:36])[CH2:34][CH2:33][CH2:32][N:26]3[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]3)=[CH:7][C:8]([CH:10]([CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:11])=[CH:9][C:4]=2[O:3]1参加物
4
実験手順
5,5-Dimethyl-8-(2-heptyl)-10-[4-(piperidino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride is prepared according to the method of Example 29 by reacting equimolar quantities of 5,5-dimethyl-8-(2-heptyl)-10-hydroxy-5H[1]benzopyrano[3,4-d]pyridine and γ-piperidinobutyric acid hydrochloride in the presence of dicyclohexyl carbodiimide.