Dicyclohexylcarbodiimide → 5,5-Dimethyl-8-methyl-10-[4-(piperidino)-butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride
反応式
[CH3:1][C:2]1([CH3:18])[C:13]2=[CH:14][CH:15]=[N:16][CH:17]=[C:12]2[C:5]2[C:6]([OH:11])=[CH:7][C:8]([CH3:10])=[CH:9][C:4]=2[O:3]1.[ClH:19].[N:20]1([CH2:26][CH2:27][CH2:28][C:29](O)=[O:30])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1.C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:19].[CH3:1][C:2]1([CH3:18])[C:13]2=[CH:14][CH:15]=[N:16][CH:17]=[C:12]2[C:5]2[C:6]([O:11][C:29](=[O:30])[CH2:28][CH2:27][CH2:26][N:20]3[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]3)=[CH:7][C:8]([CH3:10])=[CH:9][C:4]=2[O:3]1参加物
4
実験手順
5,5-Dimethyl-8-methyl-10-[4-(piperidino)-butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride is prepared according to the method of Example 29 by reacting equimolar quantities of 5,5-dimethyl-10-hydroxy-8-methyl-5H-[1]benzopyrano[3,4-d]pyridine and γ-piperidinobutyric acid hydrochloride in the presence of dicyclohexyl carbodiimide.