Dicyclohexylcarbodiimide → 5,5-Dimethyl-8-iso-propyl-10-[4-(piperidino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride
反応式
[CH3:1][C:2]1([CH3:20])[C:15]2=[CH:16][CH:17]=[N:18][CH:19]=[C:14]2[C:5]2[C:6]([OH:13])=[CH:7][C:8]([CH:10]([CH3:12])[CH3:11])=[CH:9][C:4]=2[O:3]1.[ClH:21].[N:22]1([CH2:28][CH2:29][CH2:30][C:31](O)=[O:32])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1.C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:21].[CH3:20][C:2]1([CH3:1])[C:15]2=[CH:16][CH:17]=[N:18][CH:19]=[C:14]2[C:5]2[C:6]([O:13][C:31](=[O:32])[CH2:30][CH2:29][CH2:28][N:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)=[CH:7][C:8]([CH:10]([CH3:12])[CH3:11])=[CH:9][C:4]=2[O:3]1参加物
4
実験手順
5,5-Dimethyl-8-iso-propyl-10-[4-(piperidino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride is prepared according to the method of Example 29 by reacting equimolar quantities of 5,5-dimethyl-10-hydroxy-8-iso-propyl-5H-[1]benzopyrano[3,4-d]pyridine and γ-piperidinobutyric acid hydrochloride in the presence of dicyclohexyl carbodiimide.