4-Fluorophenylboronic acid → (E)-ethyl 3-(4'-fluoro-biphenyl-4-yl)-but-2-enoate
反応式
I[C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.[F:16][C:17]1[CH:22]=[CH:21][C:20](B(O)O)=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:22]=[CH:21][C:20]([C:2]2[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=2)=[CH:19][CH:18]=1参加物
3
実験手順
The colourless solid (E)-ethyl 3-(4′-fluoro-biphenyl-4-yl)-but-2-enoate was prepared from (E)-ethyl 3-(4-iodophenyl)-but-2-enoate (example 91a) and 4-fluorobenzene boronic acid by a procedure analogous to that described in example 52a.
出典と根拠
- ORDレコード
- ord-acf2464f6b624ed3bcecc6a244631575
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06555577B1
反応ノート
読み込み中…