化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Anhydride → Ethyl 1-acetyl-4-piperidineacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | Ethyl 2-(piperidin-4-yl)acetate | HCID 2760465 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Ethyl 1-acetyl-4-piperidineacetate | HCID 54363171 | 82% |
反応手順
A mixture of 200 parts of acetic acid anhydride, 90 parts of ethyl 4-piperidineacetate and 225 parts of methylbenzene is stirred and refluxed for 3 hours. The reaction mixture is evaporated and the residue is diluted with water. The product is extracted with methylbenzene. The extract is dried, filtered and evaporated, yielding 92 parts (82%) of ethyl 1-acetyl-4-piperidineacetate as a residue.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04254127 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-3738f18a6d774f939670885c325dad30 |
| 出典メモ | uspto-grants-1981_03 |