化工社化工社 化学情報印刷レポート · 研究参考用
2-Amino-4-methylpyridine → 2-(4-Bromophenyl)-7-methylimidazo[1,2-a]pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-4-methylpyridine | HCID 1533 | — |
| 反応物 | 4-Bromophenacyl bromide | HCID 7454 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(4-Bromophenyl)-7-methylimidazo[1,2-a]pyridine | HCID 717644 | 56.8% |
反応手順
A mixture of 2,4′-dibromoacetophenone (22.4 g) and 2-amino-4-picoline (8.68 g) in ethanol (80 mL) was heated at reflux temperature for 3 hours. The reaction mixture was cooled to ambient temperature and the crystalline solid-isolated by filtration, washed with ethanol and dried in vacuo to give the title compound (13.1 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07199117B2 |
| 出典データセット | uspto-grants-2007_04 |
| ORD ID | ord-0eb7891d007242a3b2069e7540f271dc |
| 出典メモ | uspto-grants-2007_04 |