Aniline → 2-(4-Benzylaminopropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

反応式

Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]3[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]3[CH:21]=2)=[CH:8][CH:7]=1.N[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.[CH2:29]([NH:33]CCCC)CCC>>[CH2:29]([NH:33][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]3[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]3[CH:21]=2)=[CH:8][CH:7]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

参加物

反応物 3

HCID 6115Aniline

HCID 8148Dibutylamine

HCID 142014592-(4-Chloropropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

生成物 1

HCID 208031742-(4-Benzylaminopropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

実験手順

This compound was prepared according to the procedure described in Example 1 of U.S. Pat. No. 4,727,145. using 2-(4-chloropropoxyphenyl)-8-methylimidazo[1,2-a]pyridine and aniline instead of 2-(4-chloropropoxyphenyl)-imidazo[1,2-a]pyridine and dibutylamine respectively.

後処理

customThis compound was prepared

出典と根拠

ORDレコード: ord-fd1249bcf2d14947a9be8288ce02fd56
出典データセット: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07199117B2

反応ノート

読み込み中…