化工社化工社 化学情報印刷レポート · 研究参考用
Lactic Acid → 1-Carboxyethyl 4-(hexadecylamino)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Lactic Acid | HCID 612 | — |
| 反応物 | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| 反応物 | 4-(Hexadecylamino)benzoic acid | HCID 47263 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-Carboxyethyl 4-(hexadecylamino)benzoate | HCID 23457860 | — |
反応手順
A flask containing 10.0 g. (27.7 m moles) 4-(hexadecylamino)benzoic acid, 3.3 g. (36 m moles) lactic acid, 500 mg. toluenesulfonic acid and 500 ml. toluene is equipped with a Soxhlet extractor charged with activated 4 A Linde molecular sieves. The solution is refluxed for 24 hours, during which time the Soxhlet extractor is charged twice more with fresh sieves. The hot solution is filtered and left to cool, whereupon the product separates as off-white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04254138 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-1641bf210f95403c95146351e4314664 |
| 出典メモ | uspto-grants-1981_03 |