化工社化工社 化学情報印刷レポート · 研究参考用
p-Toluenesulfonic acid → Tetrahydropyranyl 4-(hexadecylamino)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | p-Toluenesulfonic acid | HCID 6101 | — |
| 反応物 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 反応物 | 4-(Hexadecylamino)benzoic acid | HCID 47263 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Tetrahydropyranyl 4-(hexadecylamino)benzoate | HCID 23457765 | — |
反応手順
A mixture of 7 g. (19.4 m moles) 4-(hexadecylamino)-benzoic acid, 2 g. (23.8 m moles) dihydropyran and 100 mg. anhydrous p-toluenesulfonic acid in 50 ml. toluene is stirred at room temperature for 20 hours. The solution is washed with saturated sodium bicarbonate, dried, and condensed. The residue is crystallized from methylcyclohexane to white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04254138 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-5b97b065307b4273b4b790f7d8eaaaf6 |
| 出典メモ | uspto-grants-1981_03 |