4-Chloro-5-methyl-6-(4-methylphenyl)pyrimidine → Ethyl [4-({butyl[5-methyl-6-(4-methylphenyl)pyrimidin-4-yl]amino}methyl)-2-methylphenoxy]acetate
反応式
Cl[C:2]1[C:7]([CH3:8])=[C:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH2:16]([NH:20][CH2:21][C:22]1[CH:34]=[CH:33][C:25]([O:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[C:24]([CH3:35])[CH:23]=1)[CH2:17][CH2:18][CH3:19].C(N(CC1C=CC(OCC(OCC)=O)=C(C)C=1)C1C(C)=C(C2C=CC(OC)=CC=2)N=CN=1)CCC>>[CH2:16]([N:20]([CH2:21][C:22]1[CH:34]=[CH:33][C:25]([O:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[C:24]([CH3:35])[CH:23]=1)[C:2]1[C:7]([CH3:8])=[C:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)[N:5]=[CH:4][N:3]=1)[CH2:17][CH2:18][CH3:19]参加物
4
反応物 3
生成物 1
実験手順
Prepared from 4-chloro-5-methyl-6-(4-methylphenyl)pyrimidine and ethyl {4-[(butylamino)methyl]-2-methylphenoxy}acetate using the procedure of Intermediate 67.
出典と根拠
- ORDレコード
- ord-40effd639b744a36a1313a0f97941c15
- 出典データセット
- uspto-grants-2007_04
- 特許番号
- US07199239B2
反応ノート
読み込み中…