4-methyl-1H-indazol-5-ol → 5-(azepin-4-yloxy)-4-methyl-1H-indazole

HRID 1269825

反応式

HRID 1269825 の反応式
O[C@@H]1CC[C@H]([N:8]2[C:16](=O)[C:15]3[C:10](=[CH:11][CH:12]=[CH:13]C=3)C2=O)CC1.CC1C=C2C(C=NN2)=CC=1O.[CH3:30][C:31]1[C:39]([OH:40])=[CH:38][CH:37]=[C:36]2[C:32]=1[CH:33]=[N:34][NH:35]2>>[NH:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:40][C:39]2[C:31]([CH3:30])=[C:32]3[C:36](=[CH:37][CH:38]=2)[NH:35][N:34]=[CH:33]3)[CH:15]=[CH:16]1

参加物

4

反応物 3

HCID 229335464-methyl-1H-indazol-5-olHCID 229340186-methyl-1H-indazol-5-olHCID 178515016HCID 178515016、化合物

生成物 1

HCID 229335105-(azepin-4-yloxy)-4-methyl-1H-indazole

実験手順

The following compound of Example 408 was synthesized by carrying out reaction according to the method described in Example 385, except for using the cis-2-(4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione obtained in Example 323, (c) and the 4-methyl-1H-indazol-5-ol obtained in Example 402, as starting materials.

後処理

  1. customreaction

出典と根拠

ORDレコード
ord-9ab61364c48340749421189c808884a2
出典データセット
uspto-grants-2007_04
特許番号
US07199147B2

関連ノート

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