5-(azepan-4-yloxy)-4-(methylthio)-1H-indazole monohydrochloride → HCID 178477321、化合物
反応式
[OH:1][C@@H:2]1[CH2:7][CH2:6][C@H:5]([N:8]2[C:16](=[O:17])[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]2=[O:18])[CH2:4][CH2:3]1.Cl.N1CCCC(OC2C(SC)=C3C(=CC=2)NN=C3)CC1.[CH2:39]([S:41][C:42]1[C:50](O)=[CH:49][CH:48]=[C:47]2[C:43]=1[CH:44]=[N:45][NH:46]2)[CH3:40]>>[CH2:39]([S:41][C:42]1[C:50]([O:1][C@H:2]2[CH2:3][CH2:4][C@H:5]([N:8]3[C:9](=[O:18])[C:10]4[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=4)[C:16]3=[O:17])[CH2:6][CH2:7]2)=[CH:49][CH:48]=[C:47]2[C:43]=1[CH:44]=[N:45][NH:46]2)[CH3:40]参加物
4
実験手順
The title compound was synthesized by carrying out reaction according to the method described in Example 610, except for using the cis-2-(4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione obtained in Example 323, (c) and the 4-(ethylthio)-1H-indazol-5-ol obtained in Example 628, as starting materials.
後処理
- customreaction