(1S,4S,5R)-6,6-dimethyl-2-oxo-4-trichloromethyl-3-oxabicyclo[3.1.0]hexane → Cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid

反応式

ClC(Cl)(Cl)[C@@H](O)C=C(C)C.[CH3:11][C:12]1([CH3:23])[C@@H:17]2[C@H:13]1[C@@H:14]([C:19](Cl)([Cl:21])[Cl:20])[O:15][C:16]2=[O:18]>>[Cl:20][C:19]([Cl:21])=[CH:14][C@@H:13]1[C@H:17]([C:16]([OH:18])=[O:15])[C:12]1([CH3:11])[CH3:23]

参加物

反応物 2

HCID 12525224(1S,4S,5R)-6,6-dimethyl-2-oxo-4-trichloromethyl-3-oxabicyclo[3.1.0]hexane

HCID 57228828(2S)-1,1,1-trichloro-4-methyl-3-penten-2-ol

生成物 1

HCID 41507Cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid

実験手順

In the manner of Examples IA.1.(a), IA.2.(a), IA.4.(a), IA.8.(a), and IIIC., (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid is prepared from (2S)-1,1,1-trichloro-4-methyl-3-penten-2-ol via (1S,4S,5R)-6,6-dimethyl-2-oxo-4-trichloromethyl-3-oxabicyclo[3.1.0]hexane.

出典と根拠

ORDレコード: ord-a5d138a9e31c468583163ec5eb9b5501
出典データセット: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04254282

反応ノート

読み込み中…

参加物