Hydrazine → O-(naphthalen-1-ylmethyl)hydroxylamine
反応式
[C:1]1([CH2:11][O:12][N:13]2C(=O)C3=CC=CC=C3C2=O)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.NN>CCO>[C:1]1([CH2:11][O:12][NH2:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
N-(1-naphthyl)methoxy phthalimide (1.21 g) was suspended in 95% EtOH and hydrazine (0.20 mL) was added. The reaction mixture was stirred overnight and then filtered. The filtrate was concentrated under reduced pressure and then taken up in a small amount of dichloromethane. The small amount of remaining phthalhydrazide was then removed by filtration. The filtrate was concentrated under reduced pressure to give the title compound (480 mg) as a colorless oil. MS(CI) m/e 174 (M+H)+.
後処理
- filtrationfiltered
- concentrationThe filtrate was concentrated under reduced pressure
- customThe small amount of remaining phthalhydrazide was then removed by filtration
- concentrationThe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-bbb41a4ded9041cabae7f2f589e8c892
- 出典データセット
- uspto-grants-2007_04
- 特許番号
- USRE039591E1
反応ノート
読み込み中…