Aluminium lithium hydride → HCID 69360623、化合物

反応式

[CH3:1][C@H:2]1[N:14]2[C:6](=[CH:7][C:8]3[C:13]2=[N:12][CH:11]=[C:10]([CH3:15])[CH:9]=3)[C:5](=O)[NH:4][CH2:3]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH3:1][C@H:2]1[N:14]2[C:6](=[CH:7][C:8]3[C:13]2=[N:12][CH:11]=[C:10]([CH3:15])[CH:9]=3)[CH2:5][NH:4][CH2:3]1

参加物

反応物 2

HCID 21226445Aluminium lithium hydride

HCID 69357943HCID 69357943、化合物

生成物 1

HCID 69360623HCID 69360623、化合物

実験手順

This compound was prepared in analogy to Example 3, intermediate l) from (R)-4,7-dimethyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one and lithium aluminium hydride. The product was purified by column chromatography over silica gel (0.030–0.063 mm) with ethyl acetate:methanol (9:1, then 3:1) as eluant.

後処理

customThe product was purified by column chromatography over silica gel (0.030–0.063 mm) with ethyl acetate:methanol (9:1

出典と根拠

ORDレコード: ord-c99e05e50f0f4a1e89796448ce524d33
出典データセット: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07208494B2

反応ノート

読み込み中…

参加物