Methyl Isocyanate → 2-oxo-4,5-dimethyl-5-ethyl-3-thiazoline-O-(methylcarbamoyl)-oxime

反応式

[N:1](=[C:3]1[N:7]=[C:6]([CH3:8])[C:5]([CH3:11])([CH2:9][CH3:10])[S:4]1)[OH:2].[CH3:12][N:13]=[C:14]=[O:15]>>[CH3:12][NH:13][C:14]([O:2][N:1]=[C:3]1[N:7]=[C:6]([CH3:8])[C:5]([CH3:11])([CH2:9][CH3:10])[S:4]1)=[O:15]

参加物

反応物 2

HCID 12228Methyl Isocyanate

HCID 859972462-Oxo-4,5-dimethyl-5-ethyl-3-thiazoline-oxime

生成物 1

HCID 867375672-oxo-4,5-dimethyl-5-ethyl-3-thiazoline-O-(methylcarbamoyl)-oxime

実験手順

2-oxo-4,5-dimethyl-5-ethyl-3-thiazoline-oxime was reacted with methyl isocyanate as described in Example 4 to yield 2-oxo-4,5-dimethyl-5-ethyl-3-thiazoline-O-(methylcarbamoyl)-oxime, m.p. 115°-117° C. The 2-oxo-4,5-dimethyl-5-ethyl-3-thiazoline-oxime starting material melts at 143.5°-144.5° C.

出典と根拠

ORDレコード: ord-90b4a360126f40f9a9ed4a3d8bcb7040
出典データセット: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04255436

反応ノート

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