化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 7-Ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 7-Ethylsulfonyl-1,4-benzodioxane-5-carboxylic acid | HCID 20544758 | — |
| 触媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 7-Ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544728 | 100% |
反応手順
243 g of thionyl chloride, a few drops of dimethyl formamide and 139 g of 7-ethylsulfonyl-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated and then the thionyl chloride in excess was distilled off under vacuum. 148 g of 7-ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 146°-147° C.; yield: 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04255580 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-5ad8f432a3ea43a79e993b8f5e28d15d |
| 出典メモ | uspto-grants-1981_03 |