Hydrochloric Acid → 5-Pyrazin-2-yl-1H-pyrimidine-2,4-dione hydrochloride
反応式
C[O:2][C:3]1[N:8]=[C:7]([O:9]C)[C:6]([C:11]2[CH:16]=[N:15][CH:14]=[CH:13][N:12]=2)=[CH:5][N:4]=1.[ClH:17]>O1CCOCC1>[ClH:17].[N:12]1[CH:13]=[CH:14][N:15]=[CH:16][C:11]=1[C:6]1[C:7](=[O:9])[NH:8][C:3](=[O:2])[NH:4][CH:5]=1参加物
4
実験手順
2,4-Dimethoxy-5-pyrazin-2-yl-pyrimidine (Prep124, 481 mg, 2.19 mmol) was dissolved in 4M HCl in dioxane solution (7 ml). After refluxing the reaction mixture for 1 hour, the solvent was removed under vacuum to give the title compound (quantitative yield)
後処理
- temperatureAfter refluxing the reaction mixture for 1 hour
- customthe solvent was removed under vacuum
出典と根拠
- ORDレコード
- ord-acd790e96df7459bb8e6de5a9519bbe7
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07727988B2
反応ノート
読み込み中…