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Methyl 2-nitroacetate → 5-Dimethylamino-2-nitro-4-[4-methyl-2-nitrophenyl]-2,4-pentadienoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-nitroacetate | HCID 17206 | — |
| 反応物 | 3-Dimethylamino-2-[4-methyl-2-nitrophenyl]acrolein | HCID 53688648 | — |
| 溶媒 | Acetic Anhydride | HCID 7918 | — |
| 生成物 | 5-Dimethylamino-2-nitro-4-[4-methyl-2-nitrophenyl]-2,4-pentadienoic acid methyl ester | HCID 53861862 | 78% |
反応手順
A mixture of 67.5 g (0.29 mol) of the compound of Example 15 and 34.3 g (0.29 mol) of methyl nitroacetate in 540 ml of acetic anhydride was heated at 60° for 2 hours. The product was worked up and recrystallized from benzene-DMF (3:1) affording 75.1 g (78%) of product as red orange crystals, m.p. 213°-215°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04256641 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-322c02f2188e442ca2e0dd6c6fcd1e21 |
| 出典メモ | uspto-grants-1981_03 |