Acetone → HCID 20284830、化合物
反応式
[NH2:1][CH2:2][CH:3]1[C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[NH:8][C:7]=2[S:6][CH2:5][CH2:4]1.[CH3:16][C:17]([CH3:19])=O>>[C:17](=[N:1][CH2:2][CH:3]1[C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[NH:8][C:7]=2[S:6][CH2:5][CH2:4]1)([CH3:19])[CH3:16]参加物
3
反応条件
- 温度
- 50 °C
実験手順
A solution of 4-aminomethyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole (1.0 g) in acetone (10 ml) is kept at room temperature for 30 minutes and then heated at 50° C. for 5 minutes. The solution is cooled with ice. The colorless precipitate is collected by filtration to give 4-isopropylideneaminomethyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole (1.07 g) melting at 173° C. (decomp.).
後処理
- temperatureThe solution is cooled with ice
- filtrationThe colorless precipitate is collected by filtration
出典と根拠
- ORDレコード
- ord-fc5f5bafeac746ba955f7fee1b028f4a
- 出典データセット
- uspto-grants-1981_03
- 特許番号
- US04256640
反応ノート
読み込み中…