5-Bromomethyl-2-furancarboxylic acid ethyl ester → (+/-)-5-[[3,4-Dihydro-5-{2-methyl-8-[l-methylethyl]-5H-dibenzo[a,d]cyclohepten-5-yl}-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-2-furancarboxylic acid, ethyl ester

関与物質

反応手順

The subtitle compound was prepared from the product of step (vi) (1 g) and 5-bromomethyl-2-furancarboxylic acid ethyl ester (J. Chem. Soc. Perkin Trans. 1, 1981, 1125, Bull. Chem. Soc. Jpn. 1987, 60, 1807)(0.65 g) according to the method of example 1 step (iv). Purification was by chromatography eluting with 20% ethyl acetate in toluene. Yield 0.375 g.

情報源と証拠