(5-Methylpyridin-2-yl)methanol → 2-Pyridinemethanol, 5-ethyl-

HRID 1276069ノート

反応式

HRID 1276069 の反応式
OCC1C=CC(C)=CN=1.C([O:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][N:16]=1)(=O)C>>[OH:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][N:16]=1

参加物

3

反応物 2

HCID 12325387(5-Methylpyridin-2-yl)methanolHCID 14346253(5-Ethylpyridin-2-yl)methyl acetate

生成物 1

HCID 30139422-Pyridinemethanol, 5-ethyl-収率 85%

実験手順

This synthesis was performed analogously to the synthesis reported for 2-hydroxymethyl-5-methyl pyridine. Starting from 2-acetoxymethyl-5-ethyl pyridine (40 g, 223 mmol), pure 2-hydroxymethyl-5-ethyl pyridine (26.02 g, 189 mmol, 85%) was obtained as a slightly yellow oil.

出典と根拠

ORDレコード
ord-281d65d3f1b4486fb75b892a9482bc7e
出典データセット
uspto-grants-2000_12
特許番号
US06165963

反応ノート

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