化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Peroxide → H-Gly-Gly-Phe-Met(O2)-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-OH
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Peroxide | HCID 784 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | gamma-endorphin, des-Tyr(1)- | HCID 3035192 | — |
| 反応物 | 2-Methylpropan-2-ol--water (1/1) | HCID 71401949 | — |
| 触媒 | Diammonium molybdate | HCID 61578 | — |
| 溶媒 | Acetate | HCID 175 | — |
| 生成物 | H-Gly-Gly-Phe-Met(O2)-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-OH | HCID 131712124 | — |
反応手順
200 mg of the peptide obtained in Example I is introduced into 5 ml water after which 0.025 ml 0.5 M ammonium molybdate, 0.125 ml HClO4 and 0.075 ml 30% hydrogen peroxide are added. The mixture is stirred for about 4 hours at room temperature, after which 5 ml tert. butanol/water (1:1) and an ion exchange resin in acetate form are added. After stirring for about 30 minutes, the ion exchange resin is separated by filtration and the filtrate is evaporated to dryness.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04256736 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-2a341be9cf174b93bee52dc29bc0c541 |
| 出典メモ | uspto-grants-1981_03 |