Acetone → 3-(Methylsulfonyl)benzenesulfonamide

HRID 1276524ノート

反応式

HRID 1276524 の反応式
CS[C:3]1[CH:4]=[C:5]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:6]=[CH:7][CH:8]=1.OO[S:15]([O-:17])=[O:16].[K+].[CH3:19]C(C)=O>>[CH3:19][S:15]([C:7]1[CH:6]=[C:5]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:4]=[CH:3][CH:8]=1)(=[O:17])=[O:16]

参加物

4

反応物 3

HCID 180AcetoneHCID 18461638HCID 18461638、化合物HCID 23707502Potassium hydroxy sulfite

生成物 1

HCID 136682473-(Methylsulfonyl)benzenesulfonamide

実験手順

To a solution of 3-methylsulfanylbenzenesulfonamide (500 mg, 2.5 mmol) in acetone was added an aqueous solution of OXONE (3.2 grams, 5 mmol). The mixture was stirred at room temperature for 12 hours. The reaction was evaporated to dryness in vacuo. The residue was triturated with acetone and filtered. The filtrated was evaporated to give 460 mg of the titled compound.

後処理

  1. customThe reaction was evaporated to dryness in vacuo
  2. customThe residue was triturated with acetone
  3. filtrationfiltered
  4. customThe filtrated was evaporated

出典と根拠

ORDレコード
ord-e03dc7965cad4f6bac233f4eed9e81e8
出典データセット
uspto-grants-2000_12
特許番号
US06166064

反応ノート

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