Ethanol → Ethyl difluoro(iodo)acetate

反応式

S(F)([O:4][C:5](F)(F)[C:6]([I:9])([F:8])[F:7])(=O)=O.[F-].[K+].[CH2:15]([OH:17])[CH3:16]>>[I:9][C:6]([F:8])([F:7])[C:5]([O:17][CH2:15][CH3:16])=[O:4]

参加物

反応物 3

HCID 702Ethanol

HCID 522689Potassium Fluoride

HCID 125963651,1,2,2-Tetrafluoro-2-iodoethyl sulfurofluoridate

生成物 1

HCID 2737200Ethyl difluoro(iodo)acetate収率 74%

実験手順

Ethyl iododifluoroacetate (73.4 g, 74% yield) could also be prepared from 2-iodo-1,1,2,2-tetrafluoroethyl fluorosulfate (130.4 g, 0.4 mol), potassium fluoride (23.2 g, 0.4 mol) and ethanol (150 mL) according to the procedure described in Experiment (3a).

出典と根拠

ORDレコード: ord-ac45c7189159486da81ca204f8df001a
出典データセット: uspto-grants-2000_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06166157

反応ノート

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