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Benzyl Bromide → 1-(Phenylmethyl)-1H-1,2,4-triazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | 1H-1,2,4-Triazole | HCID 9257 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 1-(Phenylmethyl)-1H-1,2,4-triazole | HCID 22458 | — |
反応手順
A mixture of 34.2 parts by weight of benzyl bromide, 13.8 parts by weight of 1,2,4-triazole and 41.4 parts by weight of potassium carbonate in 150 parts by weight of acetonitrile is refluxed for 10 hours while stirring. The mixture is filtered and the filtrate is evaporated to dryness and recrystallized from a mixture of toluene and cyclohexane. There is obtained 21 parts by weight of 1-benzyl-1,2,4-triazole; m.p.: 58° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04256754 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-26e929fcdfca4b17826444a9104df6a9 |
| 出典メモ | uspto-grants-1981_03 |