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Ethylene Glycol → Tertiary butoxymethyl diethylene glycol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylene Glycol | HCID 174 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 2-((1,1-Dimethylethoxy)methyl)oxirane | HCID 24314 | — |
| 触媒 | Boron trifluoride etherate | HCID 8000 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Tertiary butoxymethyl diethylene glycol | HCID 20285608 | 71% |
反応手順
To a solution of ethylene glycol (248 g, 4 moles) and boron trifluoride etherate catalyst (1 ml) in dichloromethane (20 ml) preheated to 45° C. was added t-BGE (130 g, 1 mole) dropwise at such a rate so as to maintain a gentle reflux. After completion of addition, stirring was continued for about 15 hours. The solution was then adjusted to pH 7.5 by addition of sodium hydroxide and the product removed by distillation. Tertiary butoxymethyl diethylene glycol was obtained in 71 percent yield having a boiling point of 105° C.-115° C./1 mm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04256859 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-203857138ae24d558113da98a74e02ca |
| 出典メモ | uspto-grants-1981_03 |