Hydrochloric Acid → HCID 23453834、化合物

反応式

[CH:1]([NH:4][CH2:5][CH:6]([OH:21])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)([CH3:3])[CH3:2].[ClH:22]>>[Cl-:22].[CH:1]([NH2+:4][CH2:5][CH:6]([OH:21])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)([CH3:3])[CH3:2]

参加物

反応物 2

HCID 313Hydrochloric Acid

HCID 12944288HCID 12944288、化合物

生成物 1

HCID 23453834HCID 23453834、化合物

実験手順

Following a precedure similar to that of Example 32, 1,2-epoxy-4-(1,1'-biphenyl-2-yl)butane was reacted with isopropylamine to provide N-isopropyl-2-hydroxy-4-(1,1'-biphenyl-2-yl)butylamine. The amine base so formed was reacted with hydrogen chloride to provide N-isopropyl-2-hydroxy-4-(1,1'-biphenyl-2-yl)butylaminium chloride. M.P. 153°-154° C.

出典と根拠

ORDレコード: ord-ba277840df3b49028a992dc0c1c986ff
出典データセット: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04277471

反応ノート

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